Should You Take AMPED Power and e+ Shot Together?

2018-08-06T10:19:01+00:00December 3rd, 2015|Energy, FAQ, Nutrient Timing, Product Resources, Vitality + Well-Being|

Saying you’ll exercise more is easier said than done. Once you’ve managed to get to the gym, the next difficult step is making sure your workout is intense and long enough. To ensure you’re getting the most out of your workout, a pre-workout product with a powerful boost to get you to the gym and through a difficult workout is key.

Two pre-workout options that Isagenix offers are e+™ and AMPED™ Power. Isagenix users often ask whether the two products can be taken together. The good news is that they can both work on their own, but you can maximize results from using them together. Each product is comprised of its own unique blend of ingredients that can synergistically enhance your workout regimen.

e+ Energy Shot

e+ is a naturally caffeinated energy shot different from typical energy shots. It’s free of artificial colors, sweeteners, and flavors. Compared to other energy shots, e+ contains a moderate amount of caffeine, so there are no crazy jitters or energy crashes after taking it. The caffeine itself is derived from green tea and yerba mate. Plus, it contains a blend of adaptogenic botanicals that prime the body for increased mental focus and physical activity.

Numerous studies have shown that caffeine consumption prior to any type of exercise leads to a significant improvement in overall performance (1-3). Research has also found that those who consumed caffeine prior to exercise perceived the activity as less difficult and more enjoyable (4).

Adaptogens help the body adapt to exercise by helping to reduce and resist the effects of stress while also improving the body’s capacity to perform and function under stressful circumstances (5, 6). Because exercise exists as an actual positive form of stress, your body requires the right nutritional support to be able to best handle and recover from it. Adaptogens are part of that support.


AMPED Power is a targeted pre-workout drink designed with active ingredients that work together to increase the amount of cellular energy in working muscles, while improving blood flow to allow more oxygen delivery to those muscles. The product’s ingredients include safe and effective doses of creatine monohydrate, Nitrosigine®*, and citrulline.

The creatine in AMPED Power is what works to actively increase cellular energy (as adenosine triphosphate, or ATP) in working muscles, meaning you will be able to work out longer and harder (7). The Nitrosigine® component combines the amino acid arginine and silicon to boost blood flow and improve delivery of oxygen to the muscles. Citrulline is the active ingredient that not only aids in supporting better blood flow, but also helps protect against muscle soreness (8).

The result from using AMPED Power before a workout is increased power output, decreased fatigue, improved blood flow, accelerated muscle gains, and improved performance. But when AMPED Power is taken alongside (or a half hour before) e+, the combo can work together to provide greater energy before and throughout your workout.

*Nitrosigine® is a registered trademark of Nutrition 21, LLC and is patent protected.


  1. Kamimori GH, McLellan TM, Tate CM, Voss DM, Niro P, Lieberman HR. Caffeine improves reaction time, vigilance and logical reasoning during extended periods with restricted opportunities for sleep. Psychopharmacology. 2015, 232(12), 2031–2042.
  2. Hogervorst E, Bandelow S, Schmitt J, Jentjens R, Oliveira M, Allgrove J, Carter T, Gleeson M. Caffeine improves physical and cognitive performance during exhaustive exercise. Med Sci Sports Exerc. 2008 Oct;40(10):1841-51. doi: 10.1249/MSS.0b013e31817bb8b7.
  3. Duncan MJ, Oxford SW. The effect of caffeine ingestion on mood state and bench press performance to failure. J Strength Cond Res. 2011 Jan;25(1):178-85. doi: 10.1519/JSC.0b013e318201bddb.
  4. Schubert MM, Hall S, Leveritt M, Grant G, Sabapathy S, Desbrow B. Caffeine consumption around an exercise bout: effects on energy expenditure, energy intake, and exercise enjoyment. J Appl Physiol (1985). 2014 Oct 1;117(7):745-54. doi: 10.1152/japplphysiol.00570.2014.
  5. Panossian A, Wikman G. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol, 2009;4:198-219
  6. Panossian A, Wikman G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress—protective activity. Pharmaceuticals, 2010;3:188-224. doi: 10.3390/ph3010188
  7. Van Loon LJ, Murphy R, Oosterlaar AM, Cameron-Smith D, Hargreaves M, Wagenmakers AJ, Snow R. Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle. Clin Sci, 2004;106(1), 99-106.
  8. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res, 2010;24(5), 1215-1222.