Whether you run, bike, or swim, the number one performance factor you’re concerned with is avoiding fatigue. Entering a workout with excellent levels of energy, low levels of fatigue, and enhanced recovery is every endurance athlete’s dream. Good news: AMPED™ Power is designed to do exactly that. With the three main components of AMPED Power: Nitrosigine, citrulline, and creatine, athletes can power through their workouts with minimum fatigue and maximum performance.
AMPED Power is not just for those who lift weights, but can address the problem of fatigue with all athletes. To combat fatigue, we sought out innovative ingredients like Nitrosigine™. Nitrosigine is a unique and patented complex containing the amino acid arginine bonded to silicon, the precursor to nitric oxide. Nitric oxide increases blood flow, which helps improve oxygen and delivers nutrients to muscles. For endurance athletes like runners, that means getting more oxygen and fuel to the working tissues while removing waste products, all at a much higher rate.
Nitrosigine is shown to be significantly more bioavailable than arginine alone, making it a much more powerful ingredient for boosting nitric oxide levels and blood flow to active muscle (1). Increased vasodilation in the circulatory system also decreases “pre-load” on the heart. This is the pressure the heart must overcome to pump freshly oxygenated blood into circulation. This process helps athletes in better conserving energy during exercise.
The effects from Nitrosigine last for up to three hours. As an active ingredient in AMPED Power, Nitrosigine can reduce fatigue, improve nutrient delivery, and give valuable support to the cardiovascular system (1,2).
AMPED Power also includes citrulline for purposes similar to Nitrosigine. Citrulline is shown to improve exercise performance and to stimulate muscle synthesis by activating muscle-building pathways (3, 4). Citrulline is well tolerated, even in higher dosages, and does not cause any gastrointestinal issues like other amino acids can (5). Citrulline has been noted to reduce fatigue by aiding in creatine resynthesis and enhancing the use of branched-chain amino acids during exercise (3, 6 – 8).
The third component of AMPED Power, creatine, has the ability to improve the quality of training and stimulate better gains in training adaptation, like increasing lactate threshold (9). Creatine can also improve recovery following extensive endurance training by limiting muscle damage (10). Especially in endurance athletes, creatine can help increase energy (glycogen) storage in working muscles (11).
All of these components make AMPED Power a smart combination for endurance performance. Take one serving 30 minutes before exercise and stay fully hydrated throughout. After training, make sure to take advantage of the increased blood flow and nutrient storage by taking in carbohydrates and a fast-acting protein source.
- Komorowski J, Rood-Ojalvo S & El-Sohemy A. (2015). Arginine Silicate Supplementation Decreases Markers of Cardiovascular, Renal and Metabolic Dysfunction and Increases Markers of Vasodilation and Cardiovascular Health in Healthy Adult Males. FASEB J, 29(1 Supplement), 748-2.
- Martin KR. (2013). Silicon: The health benefits of a metalloid. In Interrelations between Essential Metal Ions and Human Diseases (pp. 451-473). Springer Netherlands.
- Pérez-Guisado J & Jakeman PM. (2010). Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res, 24(5), 1215-1222.
- Cynober L, de Bandt JP & Moinard C. (2013). Leucine and citrulline: two major regulators of protein turnover. World Rev Nutr Diet, 105:97-105.
- Moinard C, Nicolis I, Neveux N, Darquy S, Benazeth S, & Cynober L. (2008). Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study. Brit J Nutr, 99(04), 855-862.
- Bendahan D, Mattei JP, Ghattas B, Confort-Gouny S, Le Guern ME, & Cozzone PJ. (2002). Citrulline/malate promotes aerobic energy production in human exercising muscle. Brit J Sport Med, 36(4), 282-289.
- Hickner RC, Tanner CJ, Evans CA, Clark PD, Haddock A, Fortune C, & McCammon M. (2006). L-citrulline reduces time to exhaustion and insulin response to a graded exercise test. Med Sci Sports Exerc, 38(4), 660-666.
- Sureda A, Córdova A, Ferrer MD, Pérez G, Tur JA, & Pons A. (2010). L-citrulline-malate influence over branched chain amino acid utilization during exercise. Eur J Appl Physiol, 110(2), 341-351.
- Chwalbiñska-Moneta J. (2003). Effect of creatine supplementation on aerobic performance and anaerobic capacity in elite rowers in the course of endurance training. Int J Sport Nutr Exerc Metab, 13, 173-183.
- Santos RVT, Bassit RA, Caperuto EC, & Rosa LC (2004). The effect of creatine supplementation upon inflammatory and muscle soreness markers after a 30km race. Life Sci, 75(16), 1917-1924.
- Van Loon LJ, Murphy R, Oosterlaar AM, Cameron-Smith D, Hargreaves M, Wagenmakers AJ & Snow R. (2004). Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle. Clin Sci, 106(1), 99-106.